2026 Hantavirus Outbreak Associated with Cruise Ship Travel
The World Health Organization (WHO) was notified on May 2, 2026, of a possible hantavirus outbreak on the MV Hondius cruise ship in the Atlantic Ocean. By June 21, 2026, all U.S. citizens potentially exposed during the outbreak have competed their 42-day monitoring period. There were no hantavirus cases in the United States associated with this outbreak. WHO declared the outbreak over on July 2, 2026. A total of 13 cases, including 3 deaths, were associated with the outbreak. For the additional situation and updates, visit CDC’s Hantavirus Current Situation website and WHO’s website.
The 2026 outbreak was caused by a type of hantavirus called Andes virus.
- Andes virus is unique. It is the only hantavirus that has been shown to spread from person to person.
- This spread between people is rare and has only been shown to occur after people start showing symptoms.
- Signs and symptoms of hantavirus pulmonary syndrome (HPS) due to Andes virus appear 4 to 42 days after exposure.
- Andes virus is a type of hantavirus found in parts of South America and the rodents that carry Andes virus have not been found in the United States.
About Andes Virus Infection
Hantaviruses are a group of viruses that are found in some wild rodents around the world. Andes virus is a type of hantavirus found in South America.
Andes virus can spread to people in several ways:
- By contact with infected rodents or their urine, droppings or saliva
- By touching an object or surface contaminated with the virus and then touching
your nose or mouth - Through close contact with a person who is sick with Andes virus
Andes virus can cause a severe respiratory illness in people called hantavirus pulmonary syndrome (HPS). HPS is rare but often deadly illness. If you might have had contact with someone with Andes virus and you have any of the symptoms listed below, call your healthcare provider or your local health department immediately.
- Illness often begins as a flu-like illness 4-42 days after contact with the virus.
- Early symptoms can include headache, fever, muscle ache or back pain, nausea or vomiting, diarrhea, and loss of appetite.
- Symptoms can quickly worsen. Cough, shortness of breath, chest pain or tightness, and difficulty breathing might occur.
- Up to forty percent of people with HPS can die from the disease.
- There is no specific treatment for Andes infection or HPS. Supportive care includes treatment of symptoms, rest, and hydration. Early medical care at a facility with an intensive care unit can improve survival.
Resources for the public and healthcare providers are listed below.
Information for Healthcare Professionals
- DCLS Hantavirus Andes Strain Testing Guidance
- VHEMP Webinar: VDH Updates on Hantavirus and Ebola Outbreaks and Summer Preparedness on May 20, 2026
- CDC Health Alert Network (HAN) Health Advisory (05/09/26)
- CDC HAN Health Update: Testing for Potential Infection (05/18/26)
- CDC Appendix A: Type and Duration of Precautions Recommended for Selected Infections and Conditions
- CDC Hantavirus Resources for Health Care Providers
- Regional Emerging Special Pathogen Treatment Center: Andes Hantavirus Health Alert for Hospitals
- Regional Emerging Special Pathogen Treatment Center: Andes Hantavirus Health Alert for EMS
- National Emerging Special Pathogens Training & Education Center (NETEC): Hantavirus Resource Library
- NETEC: PPE Matrix for High-Consequence Infectious Diseases